Half-life

2 h

Tmax

1 h

Category

peptide

Also known as: copper peptide, ghk-copper

GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) that is best known for its role in skin remodelling and wound healing. It acts by modulating gene expression, including collagen synthesis, and has been studied extensively in topical formulations for photoaged skin. Plasma half-life is approximately 2 hours. In injection-based protocols, it is typically dosed subcutaneously for systemic effects. Users should track injection site reactions, cumulative dosing, and any changes in skin appearance or recovery time.

Mechanism

A naturally occurring copper-binding tripeptide (Gly-His-Lys). It is best characterized in skin research, where it is associated with modulation of gene expression related to collagen synthesis and tissue remodeling.

Research summary

Most robust evidence is from topical dermatology and wound-healing research. Systemic (injectable) human data are limited, and it is not an FDA-approved drug for systemic use.

Reported side effects

Topical use is generally reported as well tolerated, with occasional local irritation. Systemic safety is not well characterized due to limited human data.

Educational summary of published research. Not dosing guidance or medical advice.

Sources

GHK-Cu in skin remodeling and regeneration review · peer-reviewed review article (e.g. BioMed Research International) (2014)search PubMed for GHK-Cu skin
Copper peptide dermatology studies · peer-reviewed dermatology journals (2015)predominantly topical evidence

References

GHK-Cu reviewDOI: 10.1155/2014/516971

TrackPep 是追蹤記錄工具，只記錄你輸入的內容，絕不建議或計算用量。