CJC-1295 (no DAC) tracker
Educational reference for CJC-1295 (no DAC). Use it inside TrackPep to log doses, side effects, and rotation sites.
Half-life
0.5 h
Tmax
0.25 h
Category
peptide
Also known as: mod-grf-no-dac
> PLACEHOLDER — pending clinical review by licensed pharmacist. CJC-1295 without the drug affinity complex (DAC) is a tetra-substituted analogue of growth-hormone-releasing hormone (GHRH) designed to resist dipeptidyl peptidase IV (DPP-IV) cleavage. It retains full GHRH receptor agonism but has a very short plasma half-life of approximately 30 minutes, requiring frequent dosing or co-administration with a longer-lived GH secretagogue. Without the DAC extension, this form is also known as Mod GRF 1-29 and is the more common variant in research settings. Users should log dose timing, GH-related effects, and injection site responses to assess protocol effectiveness.
Mechanism
A GHRH analog that stimulates the GHRH receptor to promote pulsatile growth-hormone release. Variants differ by the presence of a drug-affinity complex (DAC) that extends duration of action.
Research summary
Studied as a long-acting GHRH analog in early clinical pharmacology work. It is not an FDA-approved therapeutic, and long-term human outcome data are limited.
Dosing in the literature
Early pharmacology studies used subcutaneous administration under research conditions; the DAC variant has a longer duration. No approved regimen exists and this summary does not provide dosing.
Reported side effects
Reported effects include injection-site reactions, flushing, and headache. Sustained elevation of growth hormone and IGF-1 is a monitoring consideration in a clinical context. The full profile is not established.
Stacking notes
Frequently discussed with a ghrelin-receptor secretagogue such as ipamorelin in the literature; any combination is a clinical/experimental decision.
Educational summary of published research. Not dosing guidance or medical advice.
Sources
- CJC-1295 GHRH analog pharmacology study · Journal of Clinical Endocrinology & Metabolism (2006)search PubMed for CJC-1295 growth hormone
- GHRH analog reviews · peer-reviewed review articles (2015)class context
References
- CJC-1295 PK studyDOI: 10.1210/jc.2005-1536
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